Healthy aging made possible

Resources

While XPRIZE Healthspan affects every person on the planet, the field is rapidly changing. Our teams and other outside researchers are constantly making new developments, asking better questions, and developing more advanced methodologies. To stay up to date with all of the latest news, discoveries, and methods, access these curated resources.

Healthspan Research

• Longitudinal phenotypic aging metrics in the Baltimore Longitudinal Study of Aging, open access publication in Nature Aging
• Development of clinical trials to extend healthy lifespan, open access publication in Cardiovascular Endocrinology and Metabolism 
• Extending human healthspan and longevity: a symposium report, open access publication in Annals of the New York Academy of Sciences 
• Geroscience: linking aging to chronic disease, open access publication in Cell
• Physiological geroscience: targeting function to increase healthspan and achieve optimal longevity, open access publication in The Journal of Physiology

Muscle Function

• Gait Speed and Survival in Older Adults, open access publication in JAMA
• The Study of Muscle, Mobility and Aging (SOMMA): A Unique Cohort Study 

Cognitive Function

• Cognition assessment using the NIH Toolbox, open access publication in Neurology
• It's all about cognitive trajectory: Accuracy of the cognitive charts–MoCA in normal aging, MCI, and dementia, open access publication in Journal of the American Geriatrics Society

Immune Function

• Targeting the biology of ageing with mTOR inhibitors to improve immune function in older adults: phase 2b and phase 3 randomised trials, open access publication in The Lancet, Healthy Longevity
• Targeting the hallmarks of aging to improve influenza vaccine responses in older adults, open access publication in Immunity and Aging

Economic Impact

• The Economic Value of Targeting Aging, open access paper in Nature Aging
• Aging like Struldbruggs, Dorian Gray or Peter Pan, open access paper in Nature Aging
• Health, an ageing labour force, and the economy: Does health moderate the relationship between population age-structure and economic growth?, open access publication in Social Science and Medicine
• Substantial Health and Economic Returns From Delayed Aging May Warrant a New Focus for Medical Research, publication in Health Affairs
• The Value of Life and the Rise in Health Spending, open access paper in The Quarterly Journal of Economics

Women’s Health

• Women and Health: the key for sustainable development, free article from The Lancet
• Relationship of Sedentary Behavior and Physical Activity to Incident Cardiovascular Disease: Results From the Women's Health Initiative, open access publication from Journal of the American College of Cardiology
• Using science to improve the health and well-being of older women, article in Nature Aging

Importance of Diversity in Clinical Trials

• Diversity and Inclusion in Clinical Trials, article and resource information from the National Institute on Minority Health and Health Disparities
• Why Diverse Clinical Trial Participation Matters, open access publication from the New England Journal of Medicine
• Key recommendations from the 2021 “inclusion of older adults in clinical research” workshop, open access publication in Journal of Clinical and Translational Science
• Drug Trials Snapshots: Summary Report 2022, annual report from the Food and Drug Administration Center for Drug Evaluation Research
• Enhancing Diversity and Inclusion in Clinical Trials, white paper in Clinical Pharmacology and Therapeutics